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(API) Bulk Drugs |
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| MATERIAL SAFETY DATA SHEET OF DIMENHYDRINATE |
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| 1. Substance
/ Preparation and company identification |
Use : Bulk drug
Dimenhydrinate / Diphenhydramine theoclate
Company :
Medinex Laboratories Pvt. Ltd.,
Plot No. 2&3, Survey No.277/1,
Village: Ukhrala-364005.
Taluka: Ghogha, Dist: Bhavnagar.
Gujarat. INDIA.
Emergency Information : |
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| 2. Composition
/ Information on Ingredients |
Chemical nature : Antiemetic
Dimenhydrinate :
CAS Number : 523-87-5
EEC Number : |
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| 3. Hazards identification
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Harmful if swallowed. |
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| 4. First - aid
measures |
General advice
Immediately remove contaminated clothing. If danger of loss of consciousness, place patient in recovery position and transport accordingly. Apply artificial respiration if necessary. First aid personnel should pay attention to their own safety.
If inhaled :
Keep patient calm, remove to fresh air, seek medical attention.
On skin contact :
Immediately wash thoroughly with soap and water, seek medical attention.
On contact with eyes :
Immediately wash affected eyes for at least 15 minutes under running water with eyelids held open, consult an eye specialist.
On ingestion :
Rinse mouth immediately and then drink plenty of water, seek medical attention.
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| 5. Fire - fighting
measures |
Fire :
Not considered to be fire hazard
Explosion :
Not considered to be an explosion hazard.
Suitable extinguishing media :
Water, dry extinguishing media, foam, carbon dioxide.
Special protective equipment :
Wear self-contained breathing apparatus and chemical protective clothing.
Further information :
Collect separately contaminated extinguishing water, do not allow to reach sewage
or effluent systems.
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| 6. Accidental
release measures |
Personal precautions :
Breathing protection required. Avoid contact with the skin, eyes and clothing.
Environmental precautions :
Do not empty into drains.
Methods for cleaning up or taking up :
For small amounts : Pick up with suitable appliance and dispose of.
For large amounts : Pick up with suitable appliance and dispose of.
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| 7. Handling and
storage |
Handling
Ensure thorough ventilation of stores and work areas.
Protection against fire and explosion :
PPrevent electrostatic charge - sources of ignition should be kept well clear- fire
extinguishers should be kept handy.
Storage
Further information on storage conditions : Containers should be stored tightly
sealed in a dry place. Preferably filled with Nitrogen.
Storage stability : It is stable at above storage condition till its expiry date.
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| 8. Exposure controls
and personal protection |
Personal Protective equipment
Respiratory protection :
Breathing protection if breathable aerosols / dust are formed.
Hand protection :
Chemical resistant protective gloves (EN 374)
Eye protection .:
Safety glasses with side-shields (frame goggles) EN 166.
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| 9. Physical and
chemical properties. |
Form : Crystalline Powder.
Colour : White.
Odour : odourless.
Melting point : Between 102° C & 107° C
Vapor Pressure : Data not available.
Vapor Density : Data not available.
Boiling Range : Data not available.
Solubility : Sparingly Soluble in water.
Molecular Formula : C17H21NO,C7H7ClN4O2,
Molecular Weight : 469.97
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| 10. Stability
and reactivity |
Hazardous reactions :
There is no Hazardous reactions with air.
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| 11. Toxicological
information |
LD 50 / LC 50 :
CAS No : 523-87-5.
Oral Rat, LD 50 =
Intravenous Rat, LD 50 =
Oral, mouse, LD 50 =
Carcinogenicity : ----
CAS No : 523-87-5.
IARC : --
Epidemiology : No information available.
Teratogenicity : No information available.
Reproductive Effects : No information available.
Neurotoxicity ; No information available.
Mutagenilcity ; No information available.
Other studies ; See actual entry in RTECS for complete information
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| 12. Ecological information |
No information available.
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| 13. Disposal considerations |
Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR parts 261.3. additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P - Series : None listed.
RCRA U - Series : None listed.
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| 14. Transport
information |
ADR :
Class :
Packing Group : II
Designation of goods : Dimenhydrinate
RID :
Class :
Packing Group : II
Designation of goods : Dimenhydrinate
Inland waterway transport :
Class :
Packing Group : II
Designation of goods : Dimenhydrinate
Sea transport :
Class :
Packing Group : II
Designation of goods : Dimenhydrinate
Air Transport :
Class :
Packing Group : II
Designation of goods : Dimenhydrinate
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| 15. Regulatory
information |
Regulations of the European union (Labeling) / National legislation /
Regulations
Hazard symbol : -----
Risk phrases : ----
Safety phrases :
S 24 Avoid contact with skin.
S 25 Avoid contact with eyes.
CAS No : 523-87-5
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| 16. Other
information |
Warranty:
The above information is believed to be corrected but does not purport to be all-inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We shall not be held liable for any damage resulting from handling or from contact with the above product.
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