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Adrenaline Bitartrate USP [CAS # 51-42-3]  

Specification No. : MDX/FP/02
Supersedes : NIL
Issued Date : APR’2006
Next Review Date : MAR’2008

CAS No : [51-42-3]
Chemical Formula : C9H13NO3,  C4H6O6
Molecular Weight  : 333.3
Therapeutic Category : Adernergic (Beta-adrenoceptor agonist)
Packing : 100 gm / 1.000 kg in Q.L.S.B. bag.
Storage :  Store in Tightly closed light Resistant container.
Protocols to be carried out:

SR. No. Test Limit [As per USP]
1 Appearance A white to grayish white crystalline powder.
2 Solubility Freshly soluble in water, slightly soluble in ethanol 96% practically insoluble in chloroform & in ether.
3 Identification Should Comply [Specific Optical Rotation].                     
4 Specific Rotation Between : -50˚.0 & -53.5˚.
5 Melting Range Between : 147˚ C & 152˚ C.
6 Limit of Adrenalone Not more than 0.2.
7 Limit of Norepinephrine Bitartrate By T.L.C.
8 Residual solvent Traces [IPA] Not more than :0.5 %.
9 Residue on Ignition Negligible, from 100 mg.[Not more than : 0.1 %.]
10 Loss on drying Not more than : 0.5 %.
11 Assay Between : 97.0 % & 102.0 %. Of C9H13NO3,  C4H6O6


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INDIA.
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E-mail:medinex@vsnl.com

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