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(API) Bulk Drugs

MATERIAL SAFETY DATA SHEET OF SEMICARBAZIDE HYDROCHLORIDE

1. Substance / Preparation and company identification

Use : Bulk-Drug

Semicarbazide Hydrochloride

Company :
Medinex Specialty Chemicals Pvt. Ltd.,
Plot No. 4, Survey No.277/1,
Village: Ukhrala-364005.
Taluka: Ghogha, Dist: Bhavnagar.
Gujarat. INDIA.

Emergency Information :

2. Composition / Information on Ingredients

Chemical nature : Intermediate

Semicarbazide Hydrochloride
CAS Number : 563-41-7
EEC Number : 2092470

3. Hazards identification

Toxic if swallowed.

4. First – aid measures

General advice
Immediately remove contaminated clothing. If danger of loss of consciousness, place patient in recovery position and transport accordingly. Apply artificial respiration if necessary. First aid personnel should pay attention to their own safety.

If inhaled :
Keep patient calm, remove to fresh air, seek medical attention.

On skin contact :
Immediately wash thoroughly with soap and water, seek medical attention.

On contact with eyes :
Immediately wash affected eyes for at least 15 minutes under running water with eyelids held open,consult an eye specialist.

On ingestion :
Rinse mouth immediately and then drink plenty of water, seek medical attention.

5. Fire-fighting measures

Fire :
Not considered to be fire hazard

Explosion :
Not considered to be an explosion hazard.

Suitable extinguishing media :
Water, dry extinguishing media, foam, carbon dioxide.

Special protective equipment :
Wear self-contained breathing apparatus and chemical protective clothing.

Further information :
Collect separately contaminated extinguishing water, do not allow to reach sewage or effluent systems.

6. Accidental release measures

Personal precautions :
Breathing protection required. Avoid contact with the skin, eyes and clothing.

Environmental precautions :
Do not empty into drains.

Methods for cleaning up or taking up :
For small amounts : Pick up with suitable appliance and dispose of.
For large amounts : Pick up with suitable appliance and dispose of.

7. Handling and storage

Handling
Ensure thorough ventilation of stores and work areas.

Protection against fire and explosion :
Prevent electrostatic charge - sources of ignition should be kept well clear- fire extinguishers should be kept handy.

Storage
Further information on storage conditions : Containers should be stored tightly sealed in a dry place. Preferably filled with Nitrogen.

Storage stability : It is stable at above storage condition till its expiry date.

8. Exposure controls and personal protection

Personal Protective equipment

Respiratory protection :
Breathing protection if breathable aerosols / dust are formed

Hand protection :
Chemical resistant protective gloves (EN 374)

Eye protection :
Safety glasses with side-shields (frame goggles) EN 166.

9. Physical and chemical properties.

Form : Crystals.
Colour : White.
Odour : Odourless.
Melting point : 175°C to 177°C
Vapor Pressure : Data not available.
Vapor Density : Data not available.
Boiling Range : Data not available.
Solubility : Insoluble in water.
Molecular Formula : NH2 CO NH NH2. HCl
Molecular Weight : 111.53

10. Stability and reactivity

Hazardous reactions :
There is no Hazardous reactions with air.

11. Toxicological information

LD 50 / LC 50 :
CAS No : 563-41-7
Oral, mice, LD 50 = 225 mg/kg
Carcinogenicity : --
CAS No : 563-41-7
IARC : --
Epidemiology : No information available.
Teratogenicity : No information available.
Reproductive Effects : No information available.
Neurotoxicity ; No information available.
Mutagenilcity ; No information available.
Other studies ; See actual entry in RTECS for complete information.

12. Ecological information

No information available.

13. Disposal considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR parts 261.3. additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P - Series : None listed.
RCRA U - Series : None listed.

14. Transport information

ADR :
Class : 6.1
Packing Group : III
Designation of goods : Semicarbazide Hydrochloride

RID :
Class : 6.1
Packing Group : III
Designation of goods : Semicarbazide Hydrochloride

Inland waterway transport :
Class : 6.1
Packing Group : III
Designation of goods : Semicarbazide Hydrochloride

Sea transport :
Class : 6.1
Packing Group : III
Designation of goods : Semicarbazide Hydrochloride

Air Transport :
Class : 6.1
Packing Group : III
Designation of goods : Semicarbazide Hydrochloride

15. Regulatory information

Regulations of the European union ( Labelling ) / National legislation / Regulations
Regulations

Hazard symbol : T
Risk phrases :
R 25 Toxic if swallowed
Safety phrases :
S 23 Do not inhaled gas/ fumes/vapour/spra
S 24/25 Avoid contact with skin & eyes.
S 28 After contact with skin, wash immediately with plenty of water.
S 37 Wear suitable glows.
S45 Incase of accident or if u fill unwell, seek medical advise immediately.

CAS No : 563-41-7

16. Other information

Warranty:
The above information is believed to be corrected but does not purport to be all-inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We shall not be held liable for any damage resulting from handling or from contact with the above product.

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